Printable Datasheet

Recombinant CD163 (Monocyte & Macrophage Marker) Antibody [LRP/13824R]

In Stock
Catalog Number Formulation Size Price
9961-RBM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
9961-RBM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
9961-RBM6-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cytoplasm, Nuclear pore complex, Nucleus, Perinuclear region
Gene Name
MVP
Positive Control
Present in most normal tissues
Immunogen
Recombinant fragment (around aa235-249) of the human Major Vault Protein (MVP) protein (exact sequence is proprietary)
Alternate Names
Major vault protein, LRP|VAULT1

Database Links

Entrez Gene ID
9961
SwissProt
Q14764

Additional Information

Clone
LRP/13824R
Chromosome Location
16p11.2
Mol. Weight of Antigen
99.33kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All MVP Antibodies

Functions

  • Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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