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SDS-PAGE Analysis of Purified L1TD1 Mouse Monoclonal Antibody (L1TD1/7941). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human placenta stained with L1TD1 Mouse Monoclonal Antibody (L1TD1/7941). Inset: PBS instead of primary antibody; secondary only negative control.
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol | Note |
|---|---|---|---|
| Immunohistochemistry (IHC) | 1-2ug/ml | IHC Protocol | 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes |
L1TD1 (LINE-1 type transposase domain containing 1), also known as ECAT11 (ES cell-associated protein 11), is an 865 amino acid protein that belongs to the transposase 22 family and is encoded by a gene that maps to human chromosome 1p31.3. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
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