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Lewis Y (Tumor Marker) Antibody [A70-A/A9]

Additional information

Catalog Number: MSM2-1412
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
MSM2-1412-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
MSM2-1412-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
MSM2-1412-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Lewis Y (Tumor Marker) Antibody

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Lewis Y Mouse Monoclonal Antibody (A70-A/A9).

Lewis Y (Tumor Marker) Antibody - Image 2

SDS-PAGE Analysis of Purified Lewis Y Mouse Monoclonal Antibody (A70-A/A9). Confirmation of Purity and Integrity of Antibody.

  • Flow
  • IF
  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol
Immunofluorescence (IF) 1-3ug/ml
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Species Reactivity
Human
Clone
A70-A/A9
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
N/A
Gene Name
N/A
Positive Control
Bladder or Hepatocellular Carcinoma., Colon, Lung
Immunogen
Live Ls174T cells (human colon carcinoma cell line)
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Reactivity:

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Other Information

Functions
  • N/A
Key References
  • Christensen PA, Danielczyk A, Ravn P, Stahn R, Karsten U, Goletz S. A monoclonal antibody to Lewis Y/Lewis b revealing mimicry of the histone H1 to carbohydrate structures. Scand J Immunol. 2007 Apr;65(4):362-7.
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
Not Applicable
SwissProt
N/A
Chromosome Location
Not Applicable
Mol. Weight of Antigen
Multiple
Alternate Names
N/A, N/A, Lewis Y antigen

Summary

This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis Y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-). Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.

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