Printable Datasheet

Gelsolin Antibody [GSN/13633]

In Stock
Catalog Number Formulation Size Price
2934-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2934-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2934-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed:19666512). Plays a role in ciliogenesis (PubMed:20393563).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG /
Cellular Localization
Cytoplasm, Cytoskeleton, Secreted
Gene Name
GSN
Positive Control
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells
Immunogen
Recombinant human GSN protein
Alternate Names
Gelsolin, ADF|AGEL|AMYLD4

Database Links

Entrez Gene ID
2934
SwissProt
P06396

Additional Information

Clone
GSN/13633
Chromosome Location
9q33.2
Mol. Weight of Antigen
85.7kDa
Purification
Protein A

Related Antibodies

View All GSN Antibodies

Functions

  • Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed:19666512). Plays a role in ciliogenesis (PubMed:20393563).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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