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FSH-Receptor (Ovarian Marker) Antibody [FSHR/1400]

In Stock
Catalog Number Formulation Size Price
2492-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
2492-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
2492-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Cell membrane
Gene Name
Positive Control
Uterine Carcinoma.
Immunogen
Recombinant human FSHR protein
Alternate Names
Follicle-stimulating hormone receptor, Follitropin receptor, Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; FSHRO; LGR1; ODG1; ovarian dysgenesis 1

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
FSHR/1400
Chromosome Location
2p21-p16
Mol. Weight of Antigen
75kDa

Functions

  • G protein-coupled receptor for follitropin, the follicle-stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (PubMed:24058690).

Key References

  • Beau, I., et al. 1998. The basolateral localization signal of the follicle-stimulating hormone receptor. J. Biol. Chem. 273: 18610-18616.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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