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FABP2 (Marker of Metastatic Potential in Colorectal Cancer) Antibody [FABP2/6936]

Additional information

Catalog Number: 2169-MSM6
Reactivity:

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Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
2169-MSM6-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
2169-MSM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2169-MSM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
FABP2 Antibody in Immunohistochemistry (IHC (P))

FABP2 Antibody in Immunohistochemistry (IHC (P))

Formalin-fixed, paraffin-embedded human colon stained with FABP2 Mouse Monoclonal Antibody (FABP2/6936). Inset: PBS instead of primary antibody; secondary only negative control.

FABP2 Antibody in Western Blot (WB)

FABP2 Antibody in Western Blot (WB)

Western blot analysis of human small intestine tissue lysate using FABP2 Mouse Monoclonal Antibody (FABP2/6936).

FABP2 (Marker of Metastatic Potential in Colorectal Cancer) Antibody in Western Blot (WB)

FABP2 (Marker of Metastatic Potential in Colorectal Cancer) Antibody in Western Blot (WB)

Western blot analysis of human small intestine tissue lysate using FABP2 (Marker of Metastatic Potential in Colorectal Cancer) Mouse Monoclonal Antibody (FABP2/6936).

FABP2 Antibody in Western Blot (WB)

FABP2 Antibody in Western Blot (WB)

Western blot analysis of Human Intestine, Mouse Intestine and Rat Intestine tissue lysates using FABP2 Mouse Monoclonal Antibody (FABP2/6936).

FABP2 Antibody in Western Blot (WB)

FABP2 Antibody in Western Blot (WB)

Western blot analysis of Human intestine, Mouse intestine, Rat intestine, Hamster intestine, Guinea pig intestine and Rabbit intestine tissue lysates using FABP2 Mouse Monoclonal Antibody (FABP2/6936).

FABP2 Antibody in SDS-PAGE

FABP2 Antibody in SDS-PAGE

SDS-PAGE Analysis Purified FABP2 Mouse Monoclonal Antibody (FABP2/6936). Confirmation of Integrity and Purity of Antibody.

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat
Clone
FABP2/6936
Isotype
IgG2
Light Chain
Kappa
Cellular Localization
Cytoplasm
Gene Name
FABP2
Positive Control
MOLT-4 or HEK-293 cell lines. Human Intestine
Immunogen
Recombinant full length human FABP2 protein
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Key References
  • Shabana, and S Hasnain. The Fatty Acid Binding Protein 2 (FABP2) Polymorphism Ala54Thr and Obesity in Pakistan: A Population Based Study and a Systematic Meta-Analysis. Gene., U.S. National Library of Medicine, 10 Dec. 2015, www.ncbi.nlm.nih.gov/pubmed/26238699.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
2169
SwissProt
P12104
Chromosome Location
4q26
Mol. Weight of Antigen
15.21kDa
Alternate Names
Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, FABPI; I-FABP; MGC133132, Fatty Acid-Binding Protein, Intestinal

Summary

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

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