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Ep-CAM / CD326 (Rat) Antibody [Epcam/1158]

Additional information

Catalog Number: RT171577-MSM1
Reactivity:

,

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
RT171577-MSM1-BC0
Bioreactor Concentrate
0.1ml
$259.00
RT171577-MSM1-BC1
Bioreactor Concentrate
0.5ml
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Ep-CAM / CD326 (Rat) Antibody

Formalin-fixed, paraffin-embedded Rat Lung stained with Ep-CAM Monoclonal Antibody (Epcam/1158).

Ep-CAM / CD326 (Rat) Antibody - Image 2

Formalin-fixed, paraffin-embedded Rat Colon stained with Ep-CAM Monoclonal Antibody (Epcam/1158).

EPCAM Antibody in SDS-PAGE

EPCAM Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Epithelial cell adhesion molecule Mouse Monoclonal Antibody (Epcam/1158). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Mouse, Rat
Clone
Epcam/1158
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
Cell junction, Lateral cell membrane, Tight junction
Gene Name
EPCAM
Positive Control
Recombinant full-length rat Epcam protein.
Immunogen
Recombinant full-length Rat Epcam protein
Storage & Stability
Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
Bioreactor Concentrate with 0.05% Azide. Contact us if you require it in a different format.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Key References
  • Litvinov SV et. al. J Cell Biol, 1994, 125:437-46.
  • Tsubura A et. al. J Cut Pathol, 1992, 19:73-9.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
171577
SwissProt
O55159
Chromosome Location
6q12
Mol. Weight of Antigen
40-43kDa
Alternate Names
Epithelial cell adhesion molecule, Epithelial glycoprotein 314, Protein D5.7A, Tumor-associated calcium signal transducer 1, Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TACSTD1; TROP1; Tumor-associated Calcium Signal Transducer 1, ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, Flotillin-2, M17S1 (Membrane Component, Chromosome 17, Surface Marker-1), REG-1, Reggie-1, Reggie-2

Summary

Epitopes of Epcam/1158 and Epcam/1159 monoclonal antibodies are different. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas.

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