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Recombinant Cytokeratin 19 (Pancreatic Stem Cell Marker) Antibody [rKRT19/9108]

Additional information

Catalog Number: 3880-MSM22
Host:

Reactivity:

Gene:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
3880-MSM22-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3880-MSM22-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3880-MSM22-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Cytokeratin 19 (Pancreatic Stem Cell Marker) Antibody

Formalin-fixed, paraffin-embedded human prostate cancer stained with Cytokeratin 19 Recombinant Mouse Monoclonal Antibody (rKRT19/9108). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

KRT19 Antibody in SDS-PAGE

KRT19 Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Keratin, type I cytoskeletal 19 Recombinant Mouse Monoclonal Antibody (rKRT19/9108). Confirmation of Purity and Integrity of Antibody.

Cytokeratin 19 Antibody in Western Blot (WB)

Cytokeratin 19 Antibody in Western Blot (WB)

Western Blot Analysis of Human Skin tissue lysate using Cytokeratin 19 Mouse Recombinant Monoclonal Antibody (rKRT19/9108).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
rKRT19/9108
Isotype
IgG2b
Light Chain
Kappa
Cellular Localization
Cytoplasm
Gene Name
KRT19
Positive Control
MCF-7 or HeLa cells. Breast cancer tissues. Skin.
Immunogen
Recombinant full-length human KRT19 protein.
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Key References
  • Van Eyken, P., et al. 1991. Immunocytochemistry of cytokeratins in primary human liver tumors. APMIS Suppl. 23: 77-85.
  • van der Velden, L.A., et al. 1993. Cytokeratin expression in normal and (pre)malignant head and neck epithelia: an overview. Head Neck 15: 133-146.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
3880
SwissProt
P08727
Chromosome Location
17q21.2
Mol. Weight of Antigen
40kDa
Alternate Names
Keratin, type I cytoskeletal 19, Cytokeratin-19, Keratin-19, k19; k1cs; Keratin 19 Keratin Type i 40kD; KRT19

Summary

Recognizes a protein of 40kDa, identified as cytokeratin-19 (CK19), which is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

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