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BTBD9 Antibody [BTBD9/7501]

Additional information

Catalog Number: 114781-MSM1
Host:

Reactivity:

Gene:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
114781-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
114781-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
114781-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
BTBD9 Antibody

Formalin-fixed, paraffin-embedded human fallopian tube stained with BTBD9 Mouse Monoclonal Antibody (BTBD9/7501). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

BTBD9 Antibody - Image 2

SDS-PAGE Analysis of Purified BTBD9 Mouse Monoclonal Antibody (BTBD9/7501). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Clone
BTBD9/7501
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
Nucleus. Cytoplasm.
Gene Name
BTBD9
Positive Control
Human fallopian tube|lung or lymph node.
Immunogen
Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Key References
  • Wong, C.W. et al. 1998. Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARα and Bcl-6. J. Biol. Chem. 273: 27695-27702.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
114781
SwissProt
Q96Q07
Chromosome Location
6p21.2
Mol. Weight of Antigen
69kDa
Alternate Names
BTB/POZ domain-containing protein 9, BTB/POZ domain-containing protein 9

Summary

BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.

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