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ATPase family AAA domain-containing protein 2 Antibody [PCRP-ATAD2-2A8]

In Stock
Catalog Number Formulation Size Price
29028-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
29028-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
29028-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Nucleus
Gene Name
ATAD2
Positive Control
Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors
Immunogen
Recombinant human ATAD2 protein
Alternate Names
ATPase family AAA domain-containing protein 2, ANCCA|CT137|PRO2000

Database Links

Entrez Gene ID
29028
SwissProt
Q6PL18

Additional Information

Clone
PCRP-ATAD2-2A8
Chromosome Location
8q24.13
Mol. Weight of Antigen
158.55kDa
Purification
Protein A

Related Antibodies

View All ATAD2 Antibodies

Functions

  • May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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