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Recombinant MUC5AC (Mucin 5AC / Gastric Mucin) Antibody [MUC5AC/8347R]

In Stock
Catalog Number Formulation Size Price
4586-RBM21-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
4586-RBM21-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
4586-RBM21-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed:14535999, PubMed:14718370). Interacts with H.pylori in the gastric epithelium, Barrett’s esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed:14535999).

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Secreted
Gene Name
MUC5AC
Positive Control
Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia
Immunogen
Mucin isolated from an ovarian cyst fluid
Alternate Names
Mucin-5AC, MUC5|TBM|leB|mucin

Database Links

Entrez Gene ID
4586
SwissProt
P98088

Additional Information

Clone
MUC5AC/8347R
Chromosome Location
11p15.5
Mol. Weight of Antigen
585.56kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All MUC5AC Antibodies

Functions

  • Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed:14535999, PubMed:14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed:14535999).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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