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LAMP5 (Late Endosomes Marker) Antibody [LAMP5/7642]

Additional information

Catalog Number: 24141-MSM2
Host:

Reactivity:

Gene:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
24141-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
24141-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
24141-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
LAMP5 (Late Endosomes Marker) Antibody

Formalin-fixed, paraffin-embedded human kidney stained with LAMP5 Mouse Monoclonal Antibody (LAMP5/7642). Inset: PBS instead of primary antibody; secondary only negative control.

LAMP5 (Late Endosomes Marker) Antibody - Image 2

SDS-PAGE Analysis of Purified LAMP5 Mouse Monoclonal Antibody (LAMP5/7642). Confirmation of Purity and Integrity of Antibody.

LAMP5 (Late Endosomes Marker) Antibody - Image 3

Western blot analysis of U937 cell lysate using LAMP5 Mouse Monoclonal Antibody (LAMP5/7642).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
LAMP5/7642
Isotype
IgG2
Light Chain
Kappa
Cellular Localization
Cell Surface. Lysosome.
Gene Name
LAMP5
Positive Control
Human brain.
Immunogen
Recombinant full-length human LAMP5 protein
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.
Key References
  • Febbraio, M., et al. 1990. Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein. J. Biol. Chem. 265: 18531-18537.
  • 4
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
24141
SwissProt
Q9UJQ1
Chromosome Location
20p12.2
Mol. Weight of Antigen
27/31 kDa
Alternate Names
Lysosome-associated membrane glycoprotein 5, Brain and dendritic cell-associated LAMP, Brain-associated LAMP-like protein, Lysosome-associated membrane protein 5, Lysosome-Associated Membrane Glycoprotein 5

Summary

Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-5, also known as C20orf103, is a 280 amino acid protein that belongs to the LAMP family and is mainly found in cytoplasmic vesicles of the neuronal cell body. LAMP-5 is up-regulated upon CpG activation and down-regulated up Toll-like receptor (TLR) ligands.

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