Free Shipping in the U.S. for orders over $1000.  Shop Now>>

ZBTB7C / KR-POK Antibody [PCRP-ZBTB7C-4E12]

In Stock
HuProt Validated
Catalog Number Formulation Size Price
201501-MSM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
201501-MSM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
201501-MSM4-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

May be a tumor suppressor gene. Also known as APM-1 (Affected by papillomavirus DNA integration in ME180 cells protein 1. Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Isotype / Light Chain
IgG2b /
Gene Name
Positive Control
HeLa cells.
Immunogen
Recombinant full-length human ZBTB7C protein
Alternate Names
Zinc finger and BTB domain-containing protein 7C, Affected by papillomavirus DNA integration in ME180 cells protein 1, Zinc finger and BTB domain-containing protein 36, Zinc finger protein 857C, Affected by papillomavirus DNA integration in ME180 (APM-1); ZBTB36, ZNF857C; Zinc finger and BTB domain containing 7C

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZBTB7C-4E12
Chromosome Location
18q21.1
Mol. Weight of Antigen
69kDa

Functions

  • May be a tumor suppressor gene.

Key References

  • Jeon BN, et al. KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A. Cancer Res. 2012;72(5):1137-1148.
  • Costoya JA. Functional analysis of the role of POK transcriptional repressors. Brief Funct Genomic Proteomic. 2007;6(1):8-18.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Reviews

There are no reviews yet.

Be the first to review “ZBTB7C / KR-POK Antibody”

Your email address will not be published. Required fields are marked *

PARTNERSHIP OPPORTUNITIES

We hold Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK