ZBTB7C / KR-POK [PCRP-ZBTB7C-4E12]

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Summary

May be a tumor suppressor gene. Also known as APM-1 (Affected by papillomavirus DNA integration in ME180 cells protein 1. Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers.

Product Properties & Targets

Host
Species Reactivity
Isotype
Gene Name
ZBTB7C
Mol. Weight of Antigen
69kDa
Immunogen
Recombinant full-length human ZBTB7C protein

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZBTB7C-4E12
Human Gene Symbol
ZBTB7C
Chromosome Location
18q21.1

Known Applications & Suggested Dilutions

  • Flow Cytometry (1-2ug/million cells)
  • Immunofluorescence (1-2ug/ml)
  • ,Optimal dilution for a specific application should be determined.

Key References

  • Jeon BN, et al. KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A. Cancer Res. 2012;72(5):1137-1148.
  • Costoya JA. Functional analysis of the role of POK transcriptional repressors. Brief Funct Genomic Proteomic. 2007;6(1):8-18.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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