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ZBTB7C / KR-POK Antibody [PCRP-ZBTB7C-4E12]

In Stock
HuProt Validated
Catalog Number Formulation Size Price
201501-MSM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
201501-MSM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
201501-MSM4-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

May be a tumor suppressor gene. Also known as APM-1 (Affected by papillomavirus DNA integration in ME180 cells protein 1. Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Isotype / Light Chain
IgG2b /
Gene Name
Positive Control
HeLa cells.
Immunogen
Recombinant full-length human ZBTB7C protein
Alternate Names
Zinc finger and BTB domain-containing protein 7C, Affected by papillomavirus DNA integration in ME180 cells protein 1, Zinc finger and BTB domain-containing protein 36, Zinc finger protein 857C, Affected by papillomavirus DNA integration in ME180 (APM-1); ZBTB36, ZNF857C; Zinc finger and BTB domain containing 7C

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZBTB7C-4E12
Chromosome Location
18q21.1
Mol. Weight of Antigen
69kDa

Functions

  • May be a tumor suppressor gene.

Key References

  • Jeon BN, et al. KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A. Cancer Res. 2012;72(5):1137-1148.
  • Costoya JA. Functional analysis of the role of POK transcriptional repressors. Brief Funct Genomic Proteomic. 2007;6(1):8-18.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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