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Tryptase (Mast Cell Marker) Antibody [TPSAB1/1962]

Additional information

Catalog Number: 7177-MSM2
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
7177-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
7177-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
7177-MSM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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  • Documents
  • Applications & Dilutions
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Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Clone
TPSAB1/1962
Isotype
IgG2b
Light Chain
Kappa
Cellular Localization
Secreted
Gene Name
TPSAB1
Positive Control
Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin
Immunogen
Recombinant fragment (around aa 115-233) of human TPSAB1 protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Host:

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Reactivity:

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Other Information

Functions
  • Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
7177
SwissProt
Q15661
Chromosome Location
16p13.3
Mol. Weight of Antigen
30.51kDa
Alternate Names
Tryptase alpha/beta-1, TPS1|TPS2|TPSB1|TPSB2|Tryptase-2

Summary

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

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