TRIM27 Antibody [PCRP-TRIM27-1B3]

These antibodies are validated on HuProt™ Human Protein Microarrays containing over 21,000 full-length human proteins, including the specific target of interest. LEARN MORE

Additional information

Catalog Number: 5987-MSM1
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

In Stock
Catalog Number Formulation Size Price
5987-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
5987-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
5987-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
  • Flow
  • IF

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol
Immunofluorescence (IF) 1-3ug/ml

Product Properties

Antibody Type
Host
Mouse
Species Reactivity
Clone
PCRP-TRIM27-1B3
Isotype
IgG2a
Cellular Localization
Cytoplasm, Early endosome, Nucleus, PML body
Gene Name
Positive Control
HeLa, U87 or Raji cells.
Immunogen
Recombinant full-length human TRIM27 protein
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

Related Antibodies

Other Information

Functions
Key References
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
SwissProt
Chromosome Location
6p22.1
Mol. Weight of Antigen
58.49kDa
Alternate Names
Zinc finger protein RFP, RING finger protein 76, RING-type E3 ubiquitin transferase TRIM27, Ret finger protein, Tripartite motif-containing protein 27, AW538890; DAAP-182E11.3; MGC189472; Ret finger protein; RFP transforming protein; Rfp1; RING finger protein 76; RNF76; Tripartite motif-containing protein 27; Zinc finger protein RFP

Summary

Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6;10)(p21.3;q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.

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