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Recombinant Synaptic Vesicle Protein 2 (SV2) (Marker of Neuroendocrine Cells) Antibody [SV2/9844R]

In Stock
Catalog Number Formulation Size Price
9900-RBM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
9900-RBM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
9900-RBM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)., (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction (PubMed:29649119). Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cytoplasmic vesicle, Secretory vesicle, Synaptic vesicle membrane, Presynapse
Gene Name
SV2A
Immunogen
Recombinant fragment corresponding to the n-terminal cytoplasmic domain of the human Synaptic Vesicle Protein 2 (SV2) protein
Alternate Names
Synaptic vesicle glycoprotein 2A, DEE113|SLC22B1|SV2

Database Links

Entrez Gene ID
9900
SwissProt
Q7L0J3

Additional Information

Clone
SV2/9844R
Chromosome Location
1q21.2
Mol. Weight of Antigen
82.69kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All SV2A Antibodies

Functions

  • Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)., (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction (PubMed:29649119). Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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