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Recombinant Stathmin 1 / STMN1 Antibody [rSTMN1/9255]

Additional information

Catalog Number: 3925-MSM14
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
3925-MSM14-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3925-MSM14-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3925-MSM14-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Stathmin 1 / STMN1 Antibody

Formalin-fixed, paraffin-embedded human colon carcinoma stained with Stathmin 1 Recombinant Mouse Monoclonal Antibody (rSTMN1/9255). Inset: PBS instead of primary antibody; secondary only negative control.

Recombinant Stathmin 1 / STMN1 Antibody - Image 2

SDS-PAGE Analysis of Purified Stathmin 1 Recombinant Mouse Monoclonal Antibody (rSTMN1/9255). Confirmation of Purity and Integrity of Antibody.

Stathmin 1 / STMN1 Antibody in Western Blot (WB)

Stathmin 1 / STMN1 Antibody in Western Blot (WB)

Western blot analysis of Human Brain, A431, HeLa, Jurkat and PC3 lysates using Stathmin 1 / STMN1 Recombinant Mouse Monoclonal Antibody (rSTMN1/9255).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
rSTMN1/9255
Isotype
IgG2b
Light Chain
Kappa
Cellular Localization
Cytoplasm, Cytoskeleton
Gene Name
STMN1
Positive Control
Human brain or melanoma tissue. A431, HeLa, Jurkat, PC3.
Immunogen
Recombinant fragment (around aa131-149) of the human Stathmin 1 protein (exact sequence is proprietary)
Expression System
HEK293
Purification
Protein A
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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3
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VIEW ALL ANTIBODIES

Other Information

Functions
  • Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
3925
SwissProt
P16949
Chromosome Location
1p36.11
Mol. Weight of Antigen
17.3kDa
Alternate Names
Stathmin, C1orf215|LAP18|Lag|OP18|PP17|PP19|PR22|SMN

Summary

Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

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