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Recombinant immunoglobulin lambda locus Antibody [rLLC/3777]

In Stock
Catalog Number Formulation Size Price
3535-MSM11-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3535-MSM11-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3535-MSM11-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant immunoglobulin lambda locus Antibody

Formalin-fixed, paraffin-embedded human Tonsil stained with Lambda Light Chain Recombinant Mouse Monoclonal Antibody (rLLC/3777).

Recombinant immunoglobulin lambda locus Antibody - Image 2

SDS-PAGE Analysis of Purified LLC Recombinant Mouse Monoclonal Antibody (rLLC/3777). Confirmation of Integrity and Purity of Antibody

Lambda Light Chain Antibody in Western Blot (WB)

Lambda Light Chain Antibody in Western Blot (WB)

Western Blot Analysis of Human Serum tissue lysate using Lambda Light Chain Recombinant Mouse Monoclonal Antibody (rLLC/3777).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Product Properties & Targets

Antibody Type
Recombinant Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Gene Name
IGL
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen. Human Serum.
Immunogen
Recombinant full-length human Lambda Light Chain protein
Alternate Names
immunoglobulin lambda locus

Database Links

Entrez Gene ID
3535
SwissProt

Additional Information

Clone
rLLC/3777
Expression System
HEK293 Cells
Purification
Protein G

Related Antibodies

View All IGL Antibodies

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

NeoBiotechnologies holds Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

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