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Recombinant immunoglobulin lambda locus Antibody [LLC/3778R]

Additional information

Catalog Number: 3535-RBM12
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
3535-RBM12-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3535-RBM12-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3535-RBM12-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant immunoglobulin lambda locus Antibody

Formalin-fixed, paraffin-embedded human spleen stained with Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3778R).

Recombinant immunoglobulin lambda locus Antibody - Image 2

Formalin-fixed, paraffin-embedded human spleen stained with Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3778R).

Recombinant immunoglobulin lambda locus Antibody - Image 3

SDS-PAGE Analysis of Purified Lambda Light Chain Recombinant Rabbit Monoclonal (LLC/3778R). Confirmation of Integrity and Purity of Antibody

Lambda Light Chain Antibody in Western Blot (WB)

Lambda Light Chain Antibody in Western Blot (WB)

Western Blot Analysis of Human Serum and Human Spleen tissue lysates using Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3778R).

Lambda Light Chain Antibody in Western Blot (WB)

Lambda Light Chain Antibody in Western Blot (WB)

Western Blot Analysis of Spleen tissue lysates of different species using Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3778R).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
LLC/3778R
Isotype
IgG
Light Chain
Kappa
Gene Name
IGL
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen. Human Serum.
Immunogen
Recombinant full-length human Lambda Light Chain protein
Expression System
HEK293
Purification
Protein A
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
3535
Alternate Names
immunoglobulin lambda locus

Summary

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

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