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Recombinant IgA Secretory Component / ECM1 Antibody [ECM1/2889R]

In Stock
Catalog Number Formulation Size Price
1893-RBM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
1893-RBM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
1893-RBM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant IgA Secretory Component / ECM1 Antibody

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Secretory Component Rabbit Recombinant Monoclonal (ECM1/2889R).

ECM1 Antibody in SDS-PAGE

ECM1 Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Extracellular matrix protein 1 Recombinant Rabbit Monoclonal Antibody (ECM1/2889R). Confirmation of Purity and Integrity of Antibody.

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Extracellular matrix, Extracellular space, Secreted
Gene Name
ECM1
Positive Control
lung or breast tumor., Stomach
Immunogen
Recombinant human full-length ECM1 protein
Alternate Names
Extracellular matrix protein 1, URBWD

Database Links

Entrez Gene ID
1893
SwissProt
Q16610

Additional Information

Clone
ECM1/2889R
Chromosome Location
1q21.2
Mol. Weight of Antigen
60.67kDa
Expression System
HEK293 Cells
Purification
Protein A

Related Antibodies

View All ECM1 Antibodies

Functions

  • Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

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