PARTNERSHIP OPPORTUNITIES
Formalin-fixed, paraffin-embedded human kidney stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1386).
SDS-PAGE Analysis of Purified Ferritin, Light Chain Recombinant Mouse MAb (rFTL/1386). Confirmation of Integrity and Purity of Antibody
Western Blot Analysis of human Kidney tissue lysate using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1386).
Western blot analysis of A-431 cell lysate using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1386).
Western blot analysis of Human Brain, Human Kidney, Human Liver, Human Lung, Human Spleen, A431 and HeLa lysates using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1386).
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
