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Recombinant Erythropoietin (EPO) (Marker of Placentation Disorders) Antibody [EPO/3793R]

Additional information

Catalog Number: 2056-RBM4
Gene:

Host:

Reactivity:

, , , ,

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
2056-RBM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2056-RBM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2056-RBM4-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Erythropoietin (EPO) (Marker of Placentation Disorders) Antibody

Formalin-fixed, paraffin-embedded human kidney stained with Erythropoietin Recombinant Rabbit Monoclonal Antibody (EPO/3793R).

Erythropoietin Antibody in SDS-PAGE

Erythropoietin Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified EPO Recombinant Rabbit Monoclonal Antibody (EPO/3793R). Confirmation of Purity and Integrity of Antibody

Erythropoietin Antibody in Western Blot (WB)

Erythropoietin Antibody in Western Blot (WB)

Western Blot Analysis of Human Pancreas tissue lysate using Erythropoietin Recombinant Rabbit Monoclonal Antibody (EPO/3793R).

Erythropoietin Antibody in Western Blot (WB)

Erythropoietin Antibody in Western Blot (WB)

Western Blot Analysis of Pancreas tissue lysates of different species using Erythropoietin Recombinant Rabbit Monoclonal Antibody (EPO/3793R).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Guinea Pig, Hamster, Human, Mouse, Rat
Clone
EPO/3793R
Isotype
IgG
Light Chain
Kappa
Cellular Localization
Secreted
Gene Name
EPO
Positive Control
HepG2 cells. Heart or Kidney. Human Pancreas.
Immunogen
Recombinant fragment (around aa28-162) of the human Erythropoietin (EPO) protein (exact sequence is proprietary)
Expression System
HEK293
Purification
Protein A
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass (PubMed:28283061). Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3 (PubMed:9774108).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
2056
SwissProt
P01588
Chromosome Location
7q22.1
Mol. Weight of Antigen
21.31kDa
Alternate Names
Erythropoietin, DBAL|ECYT5|EP|MVCD2

Summary

Recognizes a protein of about 37kDa, which is identified as Erythropoietin (EPO). Erythropoietin is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.

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