Trial Size Available
Carrier-Free Available
Formalin-fixed, paraffin-embedded human breast carcinoma stained with Cyclin E Recombinant Mouse Monoclonal Antibody (rCCNE1/4936).
Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with Cyclin E Recombinant Mouse Monoclonal Antibody (rCCNE1/4936).
SDS-PAGE Analysis of Purified Cyclin E Recombinant Mouse Monoclonal Antibody (rCCNE1/4936). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of HCT-116, HeLa and MCF7 cell lysates using Cyclin E Recombinant Mouse Monoclonal Antibody (rCCNE1/4936).
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol | Note |
|---|---|---|---|
| Immunohistochemistry (IHC) | 1-2ug/ml | IHC Protocol | 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes |
| Western Blot (WB) | 2-4ug/ml | Western Blot Protocol |
0
1
1
2
3
6
Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.
Should a NeoBiotechnologies antibody not meet the experimental expectations outlined on our website or datasheet, please contact our Technical Support. We unconditionally guarantee our product.
Our team of scientists are ready to help you with expert recommendations or technical assistance related to applications or product use.
Information
© 2026 NeoBiotechnologies. All Rights Reserved.
Monday-Friday: 8:00am – 8:00pm Pacific Time
