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Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody [NCAM1/9074R]

Additional information

Catalog Number: 4684-RBM36
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
4684-RBM36-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
4684-RBM36-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
4684-RBM36-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody

Formalin-fixed, paraffin-embedded human colon stained with CD56 Rabbit Recombinant Monoclonal Antibody (NCAM1/9074R). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Recombinant CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody - Image 2

SDS-PAGE Analysis of Purified CD56 Rabbit Recombinant Monoclonal Antibody (NCAM1/9074R). Confirmation of Purity and Integrity of Antibody.

CD56 (Neuronal Cell Marker) Antibody in Western Blot (WB)

CD56 (Neuronal Cell Marker) Antibody in Western Blot (WB)

Western blot analysis of Human Brain tissue lysates using CD56 Rabbit Recombinant Monoclonal Antibody (NCAM1/9074R).

CD56 (Neuronal Cell Marker) Antibody in Western Blot (WB)

CD56 (Neuronal Cell Marker) Antibody in Western Blot (WB)

Western blot analysis of Human Brain, Mouse Brain and Rat Brain tissue lysates using CD56 Rabbit Recombinant Monoclonal Antibody (NCAM1/9074R).

  • IHC
  • WB
  • Flow
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot, Flow
Species Reactivity
Human
Clone
NCAM1/9074R
Isotype
IgG
Light Chain
Kappa
Cellular Localization
Cell membrane, Secreted
Gene Name
NCAM1
Positive Control
Human colon or small intestine. Human Brain, Mouse Brain
Immunogen
Recombinant full-length human CD56 protein
Expression System
CHO
Purification
Protein A
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Functions
  • This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc., (Microbial infection) Acts as a receptor for rabies virus., (Microbial infection) Acts as a receptor for Zika virus.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
4684
SwissProt
P13591
Chromosome Location
11q23.2
Mol. Weight of Antigen
94.57kDa
Alternate Names
Neural cell adhesion molecule 1, CD56|MSK39|NCAM

Summary

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

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