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Recombinant Calretinin / Calbindin 2 (Mesothelioma Marker) Antibody [rCALB2/4689]

Additional information

Catalog Number: 794-MSM9
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
794-MSM9-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
794-MSM9-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
794-MSM9-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Calretinin Antibody in Western Blot (WB)

Calretinin Antibody in Western Blot (WB)

Western Blot Analysis of Human Brain tissue lysate using Calretinin Recombinant Mouse Monoclonal Antibody (rCALB2/4689).

Calretinin Antibody in SDS-PAGE

Calretinin Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Calretinin Recombinant Mouse Monoclonal Antibody (rCALB2/4689). Confirmation of Purity and Integrity of Antibody.

Calretinin Antibody in Western Blot (WB)

Calretinin Antibody in Western Blot (WB)

Western Blot Analysis of Brain tissue lysates of different species using Calretinin Recombinant Mouse Monoclonal Antibody (rCALB2/4689).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Recombinant Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
rCALB2/4689
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
Cell projection, Dendrite, Synapse
Gene Name
CALB2
Positive Control
Brain, Testis or Mesothelioma.
Immunogen
Recombinant fragment (around aa23-242) of the human Calretinin (Calbindin 2) protein (exact sequence is proprietary)
Expression System
HEK293
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Gene:

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Reactivity:

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Reactivity:

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
794
SwissProt
P22676
Chromosome Location
16q22.2
Mol. Weight of Antigen
31.54kDa
Alternate Names
Calretinin, CAB29|CAL2|CR

Summary

It recognizes a protein of about 29kDa, which is identified as Calretinin (also known as Calbindin 2). Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adenocarcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.

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