Trial Size Available
Carrier-Free Available
SDS-PAGE Analysis of Purified Aciculin Rabbit Monoclonal Antibody (PGM5/7005R). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human tonsil prostate with Aciculin Rabbit Monoclonal Antibody (PGM5/7005R) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
Western Blot Analysis of Human Kidney, Human Skeletal muscle and PC3 lysates using Aciculin Recombinant Rabbit Monoclonal Antibody (PGM5/7005R).
Western Blot Analysis of Kidney and Skeletal muscle tissue lysates of different species using Aciculin Recombinant Rabbit Monoclonal Antibody (PGM5/7005R).
Western Blot Analysis of Kidney tissue lysates of different species using Aciculin Recombinant Rabbit Monoclonal Antibody (PGM5/7005R).
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol | Note |
|---|---|---|---|
| Immunohistochemistry (IHC) | 1-2ug/ml | IHC Protocol | 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes |
| Western Blot (WB) | 2-4ug/ml | Western Blot Protocol |
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Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
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