IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) [1B1.3a]



This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Product Properties & Targets

Species Reactivity
Cellular Localization
Gene Name
Mol. Weight of Antigen
Purified recombinant extracellular region of Mouse IL10RA

Database Links

Entrez Gene ID

Additional Information

Chromosome Location
9 A5.2; 9 24.84 cM (Mouse)

Known Applications & Suggested Dilutions

  • Neutralization Studies (Order Ab without Azide)
  • Flow Cytometry (0.5-1ug/million cells in 0.1ml)
  • Immunofluorescence (1-2ug/ml)
  • Optimal dilution for a specific application should be determined.

Key References

  • Wang W, et al. 2004. FASEB J. 18:1043. (Neutralization
  • Vieira PL, et al. 2004. J. Immunol. 172:5986. (Neutralization)

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.


This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.


There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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