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Homeobox protein SIX5 Antibody [PCRP-SIX5-2H4]

In Stock
Catalog Number Formulation Size Price
147912-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
147912-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
147912-MSM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5′-GGTGTCAG-3′ motif present in the ARE regulatory element of ATP1A1. Binds a 5′-TCA[AG][AG]TTNC-3′ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Cytoplasm, Nucleus
Gene Name
SIX5
Positive Control
Expressed in adult but not in fetal eyes
Immunogen
Recombinant human SIX5 protein
Alternate Names
Homeobox protein SIX5, BOR2|DMAHP

Database Links

Entrez Gene ID
147912
SwissProt
Q8N196

Additional Information

Clone
PCRP-SIX5-2H4
Chromosome Location
19q13.32
Mol. Weight of Antigen
74.56kDa
Purification
Protein A

Related Antibodies

View All SIX5 Antibodies

Functions

  • Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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