Printable Datasheet

Hepatocyte nuclear factor 1-alpha Antibody [HNF1A/2086]

In Stock
Catalog Number Formulation Size Price
6927-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
6927-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
6927-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Awaiting product image

Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5′-GTTAATNATTAAC-3′ (PubMed:10966642, PubMed:12453420). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity)., (Microbial infection) Plays a crucial role for hepatitis B virus gene transcription and DNA replication. Mechanistically, synergistically cooperates with NR5A2 to up-regulate the activity of one of the critical cis-elements in the hepatitis B virus genome enhancer II (ENII).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Nucleus
Gene Name
HNF1A
Positive Control
Liver
Immunogen
Recombinant fragment (around aa 214-339) of human HNF1A protein
Alternate Names
Hepatocyte nuclear factor 1-alpha, HNF-1-alpha|HNF-1A|HNF1|HNF1alpha|HNF4A|IDDM20|LFB1|MODY3|TCF-1|TCF1

Database Links

Entrez Gene ID
6927
SwissProt
P20823

Additional Information

Clone
HNF1A/2086
Chromosome Location
12q24.31
Mol. Weight of Antigen
67.39kDa
Purification
Protein G

Related Antibodies

View All HNF1A Antibodies

Functions

  • Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:10966642, PubMed:12453420). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity)., (Microbial infection) Plays a crucial role for hepatitis B virus gene transcription and DNA replication. Mechanistically, synergistically cooperates with NR5A2 to up-regulate the activity of one of the critical cis-elements in the hepatitis B virus genome enhancer II (ENII).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

NeoBiotechnologies holds Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK
Call Us Now: 1-866-2-NEOBIO (1-866-263-6246)
NeoBiotechnologies Logo
Company Info
Antibodies
Antibody Validation
Research Areas
Resources
Newsletter Signup Updates & Sales