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G-protein-signaling modulator 1 Antibody [BICCN-GPSM1-1A8]

In Stock
Catalog Number Formulation Size Price
26086-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
26086-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
26086-MSM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Cell membrane, Cytoplasm, Cytosol, Endoplasmic reticulum membrane, Golgi apparatus membrane
Gene Name
GPSM1
Positive Control
Expressed in intestinal cells
Immunogen
Recombinant fragment (around aa 1-675) of human GPSM1 protein
Alternate Names
G-protein-signaling modulator 1, AGS3

Database Links

Entrez Gene ID
26086
SwissProt
Q86YR5

Additional Information

Clone
BICCN-GPSM1-1A8
Chromosome Location
9q34.3
Mol. Weight of Antigen
74.51kDa
Purification
Protein G

Related Antibodies

View All GPSM1 Antibodies

Functions

  • Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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