ETS1 (Marker of Tumor Metastasis) Antibody [PCRP-ETS1-1C8]

In Stock
Catalog Number Formulation Size Price
2113-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2113-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2113-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518)., Acts as a dominant-negative for isoform c-ETS-1A.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Isotype / Light Chain
IgG /
Cellular Localization
Cytoplasm, Nucleus
Gene Name
Positive Control
Highly expressed within lymphoid cells
Immunogen
Recombinant human ETS1 protein
Alternate Names
Protein C-ets-1, ETS-1|EWSR2|c-ets-1|p54

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ETS1-1C8
Chromosome Location
11q24.3
Mol. Weight of Antigen
50.41kDa
Purification
Protein A

Functions

  • Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518)., Acts as a dominant-negative for isoform c-ETS-1A.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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