EpCAM / CD326 (Epithelial Marker) Antibody

• May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

• Bjork, P., Jonsson, U., Svedberg, H., Larsson, K., Lind, P., Dillner, J., Hedlund, G., Dohlsten, M. and Kalland, T. 1993. Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glyco- protein recognized by the C215 mouse monoclonal antibody. J. Biol. Chem. 268: 24232-24241.

• https://pubmed.ncbi.nlm.nih.gov/2463074/
• https://pubmed.ncbi.nlm.nih.gov/2469722/
• https://pubmed.ncbi.nlm.nih.gov/2108441/
• https://pubmed.ncbi.nlm.nih.gov/2333300/
• https://pubmed.ncbi.nlm.nih.gov/8382772/
• https://pubmed.ncbi.nlm.nih.gov/15815621/
• https://pubmed.ncbi.nlm.nih.gov/15489334/
• https://pubmed.ncbi.nlm.nih.gov/2911574/
• https://pubmed.ncbi.nlm.nih.gov/7693697/
• https://pubmed.ncbi.nlm.nih.gov/11080501/
• https://pubmed.ncbi.nlm.nih.gov/15195135/
• https://pubmed.ncbi.nlm.nih.gov/15922867/
• https://pubmed.ncbi.nlm.nih.gov/16054130/
• https://pubmed.ncbi.nlm.nih.gov/18508581/
• https://pubmed.ncbi.nlm.nih.gov/19159218/
• https://pubmed.ncbi.nlm.nih.gov/19098912/
• https://pubmed.ncbi.nlm.nih.gov/20064925/
• https://pubmed.ncbi.nlm.nih.gov/19785009/
• https://pubmed.ncbi.nlm.nih.gov/21269460/
• https://pubmed.ncbi.nlm.nih.gov/18572020/

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4072

P16422

2p21

40-43kDa

Epithelial cell adhesion molecule, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TACSTD1; TROP1; Tumor-associated Calcium Signal Transducer 1, ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, Flotillin-2, M17S1 (Membrane Component, Chromosome 17, Surface Marker-1), REG-1, Reggie-1, Reggie-2