Cytotoxic T-lymphocyte protein 4 Antibody [CTLA4/4788]

Additional information

Catalog Number: 1493-MSM5
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

In Stock
Catalog Number Formulation Size Price
1493-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
1493-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
1493-MSM5-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
  • Flow

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol

Product Properties

Antibody Type
Host
Mouse
Applications
Species Reactivity
Clone
CTLA4/4788
Isotype
IgG2a
Light Chain
Kappa
Cellular Localization
Cell membrane
Gene Name
Positive Control
Widely expressed with highest levels in lymphoid tissues
Immunogen
Activated T cellsCTLA4 protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

Related Antibodies

Other Information

Functions
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
SwissProt
Chromosome Location
2q33.2
Mol. Weight of Antigen
24.66kDa
Alternate Names
Cytotoxic T-lymphocyte protein 4, ALPS5|CD|CD152|CELIAC3|CTLA-4|GRD4|GSE|IDDM12

Summary

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

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