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BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) Antibody [BARX1/2760]

Additional information

Catalog Number: 56033-MSM2
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
56033-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
56033-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
56033-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) Antibody

Formalin-fixed, paraffin-embedded human Pancreas stained with BARX1 Mouse Monoclonal Antibody (BARX1/2760).

BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) Antibody - Image 2

SDS-PAGE Analysis of Purified AKT1 Mouse Monoclonal Antibody (AKT1/2784). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Clone
BARX1/2760
Isotype
IgG
Light Chain
Kappa
Cellular Localization
Nucleus
Gene Name
BARX1
Positive Control
HepG2 cell lysate. Human pancreas.
Immunogen
Recombinant full-length human BARX1 protein.
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity. Binds to a regulatory module of the NCAM promoter
Key References
  • Wang, G., et al. Oncotarget. 2017 Sep 22; 8(42): 71867-71880
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
56033
SwissProt
Q9HBU1
Chromosome Location
9q22.32
Mol. Weight of Antigen
24kDa
Alternate Names
Homeobox protein BarH-like 1, BarH like homeobox 1; BarX 1; BARX homeobox 1; Homeobox protein BarH like 1

Summary

BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.

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