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CD40 / TNFRSF5 / CD40L-Receptor Antibody [CD40/6597]

In Stock
Catalog Number Formulation Size Price
958-MSM9-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
958-MSM9-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
958-MSM9-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Cell membrane, Secreted
Gene Name
CD40
Positive Control
B-cells and in primary carcinomas
Immunogen
Recombinant fragment (around aa 247-276) of human CD40 protein (exact sequence is proprietary)
Alternate Names
Tumor necrosis factor receptor superfamily member 5, Bp50|CDW40|TNFRSF5|p50

Database Links

Entrez Gene ID
958
SwissProt
P25942

Additional Information

Clone
CD40/6597
Chromosome Location
20q13.12
Mol. Weight of Antigen
30.62kDa
Purification
Protein G

Related Antibodies

View All CD40 Antibodies

Functions

  • Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

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