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Bcl2-associated agonist of cell death Antibody [BAD/12641]

Additional information

Catalog Number: 572-MSM3
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

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In Stock
Catalog Number Formulation Size Price
572-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
572-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
572-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
BAD Antibody in Western Blot (WB)

BAD Antibody in Western Blot (WB)

Western blot analysis of human brain, kidney and spleen tissue lysates using BAD Mouse Monoclonal Antibody (BAD/12641).

ARG1 Antibody in Western Blot (WB)

ARG1 Antibody in Western Blot (WB)

Western blot analysis of human brain, liver and kidney tissue lysates using ARG1 Mouse Monoclonal Antibody (BAD/12641).

  • IHC
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Clone
BAD/12641
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
Cytoplasm, Mitochondrion outer membrane
Gene Name
BAD
Positive Control
Expressed in a wide variety of tissues
Immunogen
Recombinant human BAD protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
572
SwissProt
Q92934
Chromosome Location
11q13.1
Mol. Weight of Antigen
18.39kDa
Alternate Names
Bcl2-associated agonist of cell death, BBC2|BCL2L8

Summary

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

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