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SDS-PAGE Analysis of Purified CD200R1 Mouse Monoclonal Antibody (CD200R1/6493). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of Daudi cell lysate using CD200R1 Mouse Monoclonal Antibody (CD200R1/6493).
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol |
|---|---|---|
| Western Blot (WB) | 2-4ug/ml | Western Blot Protocol |
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OX2 (CD200, MOX2), a member of the immunoglobulin superfamily (IgSF), is a 248 residue cell surface glycoprotein that is expressed in lymphoid cells, neurons and endothelium. OX2 receptor (OX2R) is a membrane protein with up to 70% of its weight derived from N-linked glycosylation; it is primarily expressed in lymphoid and neuronal tissue. Phylogenetic analysis of OX2R with respect to other leukocyte IgSF glycoproteins suggests that OXR2 and OX2 share a common ancestral protein. The cytoplasmic portion of OX2R contains NPXY motifs that are known to interact with PTB/PID binding domains. The interaction between OX2 and OX2R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.
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