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  • HuProt™ Validated, PCRP

ZNF639 / ZASC1 (Transcription Factor) Antibody [PCRP-ZNF639-2B2]

These antibodies are validated on HuProt™ Human Protein Microarrays containing over 21,000 full-length human proteins, including the specific target of interest. LEARN MORE

Additional information

Catalog Number: 51193-MSM3
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
51193-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
51193-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
51193-MSM3-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
How do I understand the HuProtTM Validation Results? Learn More
ZNF639 / ZASC1 (Transcription Factor) Antibody

Flow cytometric analysis of PFA-fixed HeLa cells. ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).

ZNF639 / ZASC1 (Transcription Factor) Antibody - Image 2

Immunofluorescence Analysis of PFA-fixed HeLa cells stained using ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2)

ZNF639 / ZASC1 (Transcription Factor) Antibody - Image 3

followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).

ZNF639 / ZASC1 (Transcription Factor) Antibody - Image 4

SDS-PAGE Analysis ZNF639 Mouse Monoclonal Antibody (PCRP-ZNF639-2B2). Confirmation of Purity and Integrity of Antibody.

  • ELISA
  • Flow
  • IF
  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol
Immunofluorescence (IF) 1-3ug/ml
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
ELISA, Flow Cytometry, Immunofluorescence, Western Blot
Species Reactivity
Human
Clone
PCRP-ZNF639-2B2
Isotype
IgG2a
Cellular Localization
Nucleus
Gene Name
ZNF639
Positive Control
Colon, HeLa cells. Human fetal gut, liver or heart.
Immunogen
Recombinant human fragment (aa 406-485) ofZNF639protein
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Binds DNA and may function as a transcriptional repressor.
Key References
  • Bogaerts S, et al. Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.Exp Cell Res, 2005 Nov 15. PMID 16182284.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
51193
SwissProt
Q9UID6
Chromosome Location
3q27.1
Mol. Weight of Antigen
56.05kDa
Alternate Names
Zinc finger protein 639, Zinc finger protein ANC_2H01, Zinc finger protein ZASC1, MGC157200; ZASC1; Zfp639; Zinc finger amplified in esophageal squamous cell carcinomas 1; Zinc finger protein 639; Zinc finger protein ANC 2H01; Zinc finger protein ZASC1; ZNF 639; Znf639; ZNF639 zinc finger protein 639

Summary

This gene encodes a member of the Kruppel-like zinc finger family of proteins. Amplification and overexpression of this gene have been observed in esophageal squamous cell carcinoma. The encoded protein has been shown to bind DNA in a sequence-specific manner and may regulate HIV-1 gene expression. Alternative splicing results in multiple transcript variants.

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