Printable Datasheet

Thymidylate Synthase (5-FU Resistance Marker) Antibody [TS/2326]

In Stock
Catalog Number Formulation Size Price
7298-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
7298-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
7298-MSM5-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Catalyzes the reductive methylation of 2′-deoxyuridine 5′-monophosphate (dUMP) to thymidine 5′-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Cytoplasm, Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, Nucleus
Gene Name
TYMS
Immunogen
Recombinant fragment (around aa 60-174) of human TYMS protein
Alternate Names
Thymidylate synthase, DKCD|HST422|TMS|TS

Database Links

Entrez Gene ID
7298
SwissProt
P04818

Additional Information

Clone
TS/2326
Chromosome Location
18p11.32
Mol. Weight of Antigen
35.72kDa
Purification
Protein G

Related Antibodies

View All TYMS Antibodies

Functions

  • Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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