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Thymidylate Synthase (5-FU Resistance Marker) Antibody [TS/2326]

Additional information

Catalog Number: 7298-MSM5
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
7298-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
7298-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
7298-MSM5-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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  • Applications & Dilutions
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Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Clone
TS/2326
Isotype
IgG2b
Light Chain
Kappa
Cellular Localization
Cytoplasm, Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, Nucleus
Gene Name
TYMS
Immunogen
Recombinant fragment (around aa 60-174) of human TYMS protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Gene:

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Reactivity:

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Gene:

Host:

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Host:

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Additional information

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Reactivity:

Gene:

Host:

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Host:

VIEW ALL ANTIBODIES

Other Information

Functions
  • Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
7298
SwissProt
P04818
Chromosome Location
18p11.32
Mol. Weight of Antigen
35.72kDa
Alternate Names
Thymidylate synthase, DKCD|HST422|TMS|TS

Summary

Catalyzes the reductive methylation of 2′-deoxyuridine 5′-monophosphate (dUMP) to thymidine 5′-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

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