Trial Size Available
Carrier-Free Available
Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Beta-2-Microglobulin Mouse Recombinant Monoclonal Antibody (rB2M/961).
Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Beta-2-Microglobulin Mouse Recombinant Monoclonal Antibody (rB/961).
Formalin-fixed, paraffin-embedded human Cervical Carcinoma stained with Beta-2-Microglobulin Mouse Recombinant Monoclonal Antibody (rB2M/961).
SDS-PAGE Analysis Beta-2-Microglobulin Mouse Recombinant Monoclonal Antibody (rB2M/961). Confirmation of Purity and Integrity of Antibody.
Flow Cytometric Analysis of PFA-fixed HeLa cells using Beta-2-Microglobulin Mouse Recombinant MAb (rB2M/961) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red)
Analysis of Protein Array containing more than 19,000 full-length human proteins using Beta-2 Microglobulin Mouse Recombinant Monoclonal Antibody (rB2M/961). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Western Blot Analysis of Human Spleen, Mouse Spleen, Rat Spleen, Human Lungs, Mouse Lungs and Rat Lungs tissue lysates using Beta-2-Microglobulin Mouse Recombinant Monoclonal Antibody (rB2M/961).
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol | Note |
|---|---|---|---|
| Immunohistochemistry (IHC) | 1-2ug/ml | IHC Protocol | 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes |
| Western Blot (WB) | 2-4ug/ml | Western Blot Protocol |
0
3
3
3
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Should a NeoBiotechnologies antibody not meet the experimental expectations outlined on our website or datasheet, please contact our Technical Support. We unconditionally guarantee our product.
Our team of scientists are ready to help you with expert recommendations or technical assistance related to applications or product use.
Information
© 2026 NeoBiotechnologies. All Rights Reserved.
Monday-Friday: 8:00am – 8:00pm Pacific Time
