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PR domain zinc finger protein 8 Antibody [PCRP-PRDM8-1A1]

In Stock
Catalog Number Formulation Size Price
56978-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
56978-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
56978-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Probable histone methyltransferase, preferentially acting on ‘Lys-9’ of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Nucleus
Gene Name
PRDM8
Positive Control
Expressed in brain, heart, skeletal muscle, testes, prostate
Immunogen
Recombinant human PRDM8 protein
Alternate Names
PR domain zinc finger protein 8, EPM10|KMT8D|PFM5

Database Links

Entrez Gene ID
56978
SwissProt
Q9NQV8

Additional Information

Clone
PCRP-PRDM8-1A1
Chromosome Location
4q21.21
Mol. Weight of Antigen
71.66kDa
Purification
Protein A

Related Antibodies

View All PRDM8 Antibodies

Functions

  • Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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