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Mesothelin (Mesothelial Marker) Antibody [MSLN/2132]

Additional information

Catalog Number: 10232-MSM2
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
10232-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
10232-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
10232-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Mesothelin Antibody in Western Blot (WB)

Mesothelin Antibody in Western Blot (WB)

Western Blot Analysis of OVCAR-3 lysate using Mesothelin Mouse Monoclonal Antibody (MSLN/2132).

Mesothelin Antibody in SDS-PAGE

Mesothelin Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified MSLN Mouse Monoclonal Antibody (MSLN/2132). Confirmation of Purity and Integrity of Antibody.

  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Clone
MSLN/2132
Isotype
IgG2b
Light Chain
Kappa
Cellular Localization
Cell membrane, Golgi apparatus, Secreted
Gene Name
MSLN
Positive Control
OVCAR-3 cells, CAPAN-2 or HeLa cells. Lung Mesothelioma.
Immunogen
Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Reactivity:

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Host:

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Additional information

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Gene:

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Reactivity:

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VIEW ALL ANTIBODIES

Other Information

Functions
  • Membrane-anchored forms may play a role in cellular adhesion.
  • Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Key References
  • Chang, K. and Pastan, I. 1996. Molecular cloning of Mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc. Natl. Acad. Sci. USA 93: 136-140.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
10232
SwissProt
Q13421
Chromosome Location
16p13.3
Mol. Weight of Antigen
40kDa (Mature form); 69kDa (Precursor)
Alternate Names
Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, CAK1; Megakaryocyte potentiating factor; Mesothelin; MSLN; SMR; SMRP

Summary

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

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