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Malate dehydrogenase 1 NAD (soluble) Antibody [CPTC-MDH1-1]

Additional information

Catalog Number: 4190-MSM1
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
4190-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
4190-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
4190-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Malate dehydrogenase 1 NAD (soluble) Antibody

SDS-PAGE Analysis of Purified MDH1 Mouse Monoclonal Antibody (CPTC-MDH1-1). Confirmation of Purity and Integrity of Antibody.

Malate dehydrogenase 1 NAD (soluble) Antibody - Image 2

Western Blot Analysis of HeLa, HepG2, Jurkat, HEP2, U937, PC3 cell lysates using MDH1 Mouse Monoclonal Antibody (CPTC-MDH1-1).

  • WB
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Clone
CPTC-MDH1-1
Isotype
IgG2a
Light Chain
Kappa
Cellular Localization
Cytoplasm
Gene Name
MDH1
Positive Control
Jurkat or HeLa cell lysates.
Immunogen
Recombinant human full-length MDH1 protein
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237).
Key References
  • Drmota, T., et al. 1997.. Folia Parasitol. 44: 103-108.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
4190
SwissProt
P40925
Chromosome Location
2p15
Mol. Weight of Antigen
36kDa
Alternate Names
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, HEL-S-32, MDH-s, MDHA; MDH1; soluble malate dehydrogenase

Summary

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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