IGF2BP2 Antibody [PCRP-IGF2BP2-1F9]

These antibodies are validated on HuProt™ Human Protein Microarrays containing over 21,000 full-length human proteins, including the specific target of interest. LEARN MORE

Additional information

Catalog Number: 10644-MSM1
Host:

Reactivity:

Gene:

In Stock

Trial Size Available

Carrier-Free Available

In Stock
Catalog Number Formulation Size Price
10644-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
10644-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
10644-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
  • Flow

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol

Product Properties

Antibody Type
Host
Mouse
Applications
Species Reactivity
Clone
PCRP-IGF2BP2-1F9
Isotype
IgG2
Light Chain
Kappa
Cellular Localization
Nucleus
Gene Name
Positive Control
HeLa cells.
Immunogen
Recombinant full-length human IGF2BP2 protein
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

Related Antibodies

Other Information

Functions
Key References
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
SwissProt
Chromosome Location
3q27.2
Mol. Weight of Antigen
105kDa
Alternate Names
Insulin-like growth factor 2 mRNA-binding protein 2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2, Hepatocellular carcinoma autoantigen p62; IGF 2 mRNA binding protein 2; IGF II mRNA binding protein 2; IMP2; Insulin like growth factor 2 mRNA binding protein 2; p62; VICKZ 2; VICKZ family member 2; VICKZ2

Summary

IGF2BP2 (Insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type two diabetes mellitus.

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