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IgA Secretory Component / ECM1 Antibody [ECM1/792]

Additional information

Catalog Number: 1893-MSM2
Reactivity:

,

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

download data sheet
In Stock
Catalog Number Formulation Size Price
1893-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
1893-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
1893-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
IgA Secretory Component / ECM1 Antibody

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with IgA Secretory Component Mouse Monoclonal Antibody (ECM1/792).

IgA Secretory Component / ECM1 Antibody - Image 2

SDS-PAGE Analysis of Purified IgA Secretory Component Mouse Monoclonal Antibody (ECM1/792). Confirmation of Purity and Integrity of Antibody.

  • Flow
  • IF
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol
Flow Cytometry (Flow) 1-2ug/million cells Flow Cytometry Protocol
Immunofluorescence (IF) 1-3ug/ml

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human, Rat
Clone
ECM1/792
Isotype
IgG1
Light Chain
Kappa
Cellular Localization
Extracellular matrix, Extracellular space, Secreted
Gene Name
ECM1
Positive Control
Lung, or Breast tumor., Stomach
Immunogen
Recombinant full-length human ECM1 protein
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
Key References
  • Kuhn, L.C. and Kraehenbuhl, J.P. 1980. J. Biol. Chem. 254: 11072-11081.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
1893
SwissProt
Q16610
Chromosome Location
1q21.2
Mol. Weight of Antigen
~80kDa
Alternate Names
Extracellular matrix protein 1, Secretory component p85, ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD

Summary

This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

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