Recombinant Helicobacter pylori (Catalase) [HPYL/8548R]

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Summary

The spiral shaped bacterium �Helicobacter pylori �is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. �H. pylori �is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. �This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Product Properties & Targets

Host
Species Reactivity
Isotype
Cellular Localization
Cell Surface. Cytoplasm.
Positive Control
Helicobacter pylori infected stomach biopsy
Immunogen
Recombinant Helicobacter pylori Catalase protein fragment (around aa323-445) (Exact sequence is proprietary)
Alternate Names
, H. pylori

Database Links

Entrez Gene ID
Unigene
SwissProt

Additional Information

Clone
HPYL/8548R
Human Gene Symbol
Not Applicable
Chromosome Location
Not Applicable
Mol. Weight of Antigen
58kDa

Known Applications & Suggested Dilutions

  • Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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