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Cyclin-D-binding Myb-like transcription factor 1 Antibody [PCRP-DMTF1-1A8]

In Stock
Catalog Number Formulation Size Price
9988-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
9988-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
9988-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5′-CCCG[GT]ATGT-3′ (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Nucleus
Gene Name
DMTF1
Positive Control
Expressed at relatively low levels in colonic mucosa, ovary, peripheral leukocytes, prostate and small intestine, and at higher levels in spleen, testis and thymus
Immunogen
Recombinant human DMTF1 protein
Alternate Names
Cyclin-D-binding Myb-like transcription factor 1, DMP1|DMTF|MRUL|hDMP1

Database Links

Entrez Gene ID
9988
SwissProt
Q9Y222

Additional Information

Clone
PCRP-DMTF1-1A8
Chromosome Location
7q21.12
Mol. Weight of Antigen
84.47kDa
Purification
Protein A

Related Antibodies

View All DMTF1 Antibodies

Functions

  • Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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