CDw60 (GD3) [UM4D4]

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Summary

This MAb reacts with 9-O-acetylated disialosyl group linked to the glycoprotein CD60w. CDw60 is a carbohydrate antigen present on gangliosides, platelets and a subset of CD4+, CD8+peripheral T-cells, but not on B-cells, monocytes or granulocytes. CDw60 is involved in the co-stimulation of T-cells.

Product Properties & Targets

Host
Species Reactivity
Isotype
IgM
Cellular Localization
N/A
Gene Name
N/A
Immunogen
Human rheumatoid synovial T cell line (ST-1)

Database Links

Entrez Gene ID
Unigene
SwissProt
N/A

Additional Information

Clone
UM4D4

Known Applications & Suggested Dilutions

  • ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA)
  • Optimal dilution for a specific application should be determined.

Key References

  • Fox DA et. al. in Knapp W (ed) Leucocyte Typing IV 1989; pp364-366 (Oxford University Press, London).
  • Fox DA et. al. Immunol Invest 30(2):67-85, 2001.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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