CD90 (Anti-Mouse) (Stromal / Mesenchymal Marker) [IBL-6/23]

Clear

Summary

Recognizes a protein of 25kDa, identified as mouse Thy-1 (also known as CD90). It is a glycosyl phosphatidylinositol-anchored surface glycoprotein. CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35kDa) inserted into the cell membrane via a GPI anchor. Thy-1 is expressed mainly on brain and lymphoid tissues including thymocytes, Peripheral T-cells, and some intraepithelial T-lymphocytes. Thy-1 may play a role in T cell activation, development and function of nervous system, and apoptosis.

Product Properties & Targets

Host
Rat
Species Reactivity
Isotype
Cellular Localization
Gene Name
THY1
Mol. Weight of Antigen
25kDa
Immunogen
Mouse EL-4 T cell lymphoma cells

Database Links

Entrez Gene ID
Unigene
SwissProt

Additional Information

Clone
IBL-6/23
Human Gene Symbol
Thy1
Chromosome Location
9 A5.1; 9 24.52 cM

Known Applications & Suggested Dilutions

  • Flow Cytometry (1-2ug/million cells in 0.1ml)
  • ,Immunofluorescence (1-2ug/ml)
  • ,Optimal dilution for a specific application should be determined.

Key References

  • Williams, A.F., and J. Gagnon. 1982. Neuronal cell Thy-1 glycoprotein: Homology with immunoglobulin. Science 216: 696 703
  • Fujita N, et al. Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp Cell Res 1997, 232(2):400-406

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Recombinant mouse monoclonal antibodies and recombinant rabbit monoclonals to support your research

Shop Primary Antibodies