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CD90 (Anti-Mouse) (Stromal / Mesenchymal Marker) Antibody [IBL-6/23]

In Stock
Catalog Number Formulation Size Price
MS21838-RTM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
MS21838-RTM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
MS21838-RTM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-2ug/ml

Summary

Recognizes a protein of 25kDa, identified as mouse Thy-1 (also known as CD90). It is a glycosyl phosphatidylinositol-anchored surface glycoprotein. CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35kDa) inserted into the cell membrane via a GPI anchor. Thy-1 is expressed mainly on brain and lymphoid tissues including thymocytes, Peripheral T-cells, and some intraepithelial T-lymphocytes. Thy-1 may play a role in T cell activation, development and function of nervous system, and apoptosis.

Product Properties & Targets

Antibody Type
Host
Rat
Species Reactivity
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Cell membrane
Gene Name
Positive Control
Mouse thymus.
Immunogen
Mouse EL-4 T cell lymphoma cells
Alternate Names
Thy-1 membrane glycoprotein, Thy-1 antigen, CD90; Theta antigen; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1.2; Thy-1 antigen; Thy-1 membrane glycoprotein; Thy1; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
IBL-6/23
Chromosome Location
9 A5.1; 9 24.52 cM
Mol. Weight of Antigen
25kDa

Functions

  • May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

Key References

  • Williams, A.F., and J. Gagnon. 1982. Neuronal cell Thy-1 glycoprotein: Homology with immunoglobulin. Science 216: 696 703
  • Fujita N, et al. Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp Cell Res 1997, 232(2):400-406

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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