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SDS-PAGE Analysis of Purified CD171 Mouse Monoclonal Antibody (UJ127). Confirmation of Integrity and Purity of Antibody.
SDS-PAGE Analysis Purified CD171 Mouse Monoclonal Antibody (UJ127). Confirmation of Integrity and Purity of Antibody.
SDS-PAGE Analysis of Purified Neural cell adhesion molecule L1 / L1CAM Mouse Monoclonal Antibody (UJ127). Confirmation of Purity and Integrity of Antibody.
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| Material Safety Data Sheet | Download Here |
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Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
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